Multiple comparison testing used a Bonferroni correction to

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In the trials of participants with a history of CHD there was generally no selection by blood pressure and no blood pressure target; treated patients were allocated a specified drug in fixed dose, varied only to avoid adverse effects. In the trials of participants with a history of stroke most followed the treat to target approach, some followed the specified drug approach. In trials of participants who had acute myocardial infarction on entry sudden deaths while in hospital were not recorded because it was not our objective to assess the efficacy of the drugs in reducing mortality in the period immediately after infarction; the CHD events and heart failure episodes we recorded were either those designated as reinfarction or those occurring after hospital discharge.

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